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Affinity labeling of the catalytic subunit of cyclic AMP-dependent protein kinase by N alpha-tosyl-L-lysine chloromethyl ketone.

The catalytic subunit of cyclic AMP-dependent protein kinase (from rabbit skeletal muscle; ATP:protein phosphotransferase, EC 2.7.1.37) was found to be irreversibly inactivated by chloromethyl ketone derivatives of lysine and phenylalanine, chemical reagents originally designed for labeling the acti...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Kupfer, A, Gani, V, Jiménez, J S, Shaltiel, S
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1979
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383765/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/226953/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.7.3073
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