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Targeted inhibition of BRAF kinase: opportunities and challenges for therapeutics in melanoma

Malignant melanoma is the most aggressive form of skin cancer and its incidence has increased dramatically in the past two decades. Even with a high rate of success in the treatment of early stages of this malignancy, currently there are no effective strategies for the treatment of advanced metastat...

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Detalhes bibliográficos
Main Authors: Pérez-Lorenzo, Rolando, Zheng, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837566/
https://ncbi.nlm.nih.gov/pubmed/21981139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20110068
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