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Evidence for internalization of the recognition site of β-adrenergic receptors during receptor subsensitivity induced by (-)-isoproterenol

In the supernatant (30,000 × g) of frog erythrocyte homogenates, by using gel filtration we detected a protein that could bind [(3)H]dihydroalprenolol ([(3)H]DHA) with high affinity. This binding was greatly enhanced when the erythrocytes were preincubated with (-)-isoproterenol. After various perio...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Chuang, De-Maw, Costa, E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1979
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383744/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/223168/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.6.3024
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