DNA promoter methylation in breast tumors: No association with genetic polymorphisms in MTHFR and MTR

Aberrant promoter methylation is recognized as an important feature of breast carcinogenesis. We hypothesized that genetic variation of genes for methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MTR), two critical enzymes in one-carbon metabolism, may alter DNA methylation levels...

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書誌詳細
主要な著者: Tao, Meng Hua, Shields, Peter G., Nie, Jing, Marian, Catalin, Ambrosone, Christine B., McCann, Susan E., Platek, Mary, Krishnan, Shiva S., Xie, Bin, Edge, Stephen B., Winston, Janet, Vito, Dominica, Trevisan, Maurizio, Freudenheim, Jo L.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837294/
https://ncbi.nlm.nih.gov/pubmed/19240236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-08-0916
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