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Structural evidence for independent joining region gene in immunoglobulin heavy chains from anti-galactan myeloma proteins and its potential role in generating diversity in complementarity-determining regions

We have determined the variable region sequences of four heavy chains from β(1-6)D-galactan-binding myeloma proteins. Two of these proteins are identical to position 100 which is located in the third complementarity-determining region (CDR-3). The remaining two differ at a total of 8 positions over...

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Detalhes bibliográficos
Main Authors: Rao, D. Narayana, Rudikoff, Stuart, Krutzsch, Henry, Potter, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 1979
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC383715/
https://ncbi.nlm.nih.gov/pubmed/111245
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