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An Intramolecular Chaperone Inserted in Bacteriophage P22 Coat Protein Mediates Its Chaperonin-independent Folding

The bacteriophage P22 coat protein has the common HK97-like fold but with a genetically inserted domain (I-domain). The role of the I-domain, positioned at the outermost surface of the capsid, is unknown. We hypothesize that the I-domain may act as an intramolecular chaperone because the coat protei...

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Main Authors: Suhanovsky, Margaret M., Teschke, Carolyn M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837121/
https://ncbi.nlm.nih.gov/pubmed/24126914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515312
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