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Fixation of a deleterious allele at one of two "duplicate" loci by mutation pressure and random drift.

We consider a diploid population and assume two gene loci with two alleles each, A and a at one locus and B and b at the second locus. Mutation from wild-type alleles A and B to deleterious alleles a and b occurs with mutation rates va and vb, respectively. We assume that alleles are completely rece...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Kimura, M, King, J L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1979
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383708/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/288072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.6.2858
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