Fixation of a deleterious allele at one of two "duplicate" loci by mutation pressure and random drift.
We consider a diploid population and assume two gene loci with two alleles each, A and a at one locus and B and b at the second locus. Mutation from wild-type alleles A and B to deleterious alleles a and b occurs with mutation rates va and vb, respectively. We assume that alleles are completely rece...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1979
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/288072/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.6.2858 |
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