Pancreatic Islet Vasculature Adapts to Insulin Resistance Through Dilation and Not Angiogenesis

Pancreatic islets adapt to insulin resistance through a complex set of changes, including β-cell hyperplasia and hypertrophy. To determine if islet vascularization changes in response to insulin resistance, we investigated three independent models of insulin resistance: ob/ob, GLUT4(+/−), and mice w...

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Main Authors: Dai, Chunhua, Brissova, Marcela, Reinert, Rachel B., Nyman, Lara, Liu, Eric H., Thompson, Courtney, Shostak, Alena, Shiota, Masakazu, Takahashi, Takamune, Powers, Alvin C.
Formato: Artigo
Idioma:Inglês
Publicado: American Diabetes Association 2013
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837044/
https://ncbi.nlm.nih.gov/pubmed/23630302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1657
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