Gestational Diabetes Mellitus Impairs Nrf2-Mediated Adaptive Antioxidant Defenses and Redox Signaling in Fetal Endothelial Cells In Utero

In utero exposure to gestational diabetes mellitus (GDM) is associated with an increased risk of type 2 diabetes and cardiovascular disease in later life, yet the underlying mechanisms remain to be elucidated. We examined the effects of GDM on the proteome, redox status, and nuclear factor erythroid...

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Detalhes bibliográficos
Main Authors: Cheng, Xinghua, Chapple, Sarah J., Patel, Bijal, Puszyk, William, Sugden, David, Yin, Xiaoke, Mayr, Manuel, Siow, Richard C.M., Mann, Giovanni E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837032/
https://ncbi.nlm.nih.gov/pubmed/23974919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0169
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