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Simple Sequence Repeats Together with Mismatch Repair Deficiency Can Bias Mutagenic Pathways in Pseudomonas aeruginosa during Chronic Lung Infection

Pseudomonas aeruginosa is an opportunistic pathogen that chronically infects the airways of cystic fibrosis (CF) patients and undergoes a process of genetic adaptation based on mutagenesis. We evaluated the role of mononucleotide G:C and A:T simple sequence repeats (SSRs) in this adaptive process. A...

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Detalhes bibliográficos
Main Authors: Moyano, Alejandro J., Feliziani, Sofía, Di Rienzo, Julio A., Smania, Andrea M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837008/
https://ncbi.nlm.nih.gov/pubmed/24278287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080514
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