Association between the CYP4A11 T8590C Variant and Essential Hypertension: New Data from Han Chinese and a Meta-Analysis

OBJECTIVE: CYP4A11 oxidizes endogenous arachidonic acid to 20-hydroxyeicosatetraenoic acid, a renal vasoconstrictor and natriuretic in humans. Previous studies demonstrated an association between a functional variant (T8590C) of CYP4A11 and essential hypertension, though with conflicting results. To...

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Hlavní autoři: Yan, Hua-Cheng, Liu, Jun-Hua, Li, Jian, He, Bao-Xia, Yang, Liang, Qiu, Jian, Li, Liang, Ding, Da-Peng, Shi, Lei, Zhao, Shu-Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836999/
https://ncbi.nlm.nih.gov/pubmed/24278241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080072
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