Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.

When suspension cultures of human promyelocytic leukemia cells (line HL60) were treated with 12-O-tetradecanoylphorbol 13-acetate (TPA; 1.6-160 nM), more than 80% of the cells adhered to the plastic substrate within 24 hr. Within the same time period the immature azurophilic granulations typical of...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Rovera, G, Santoli, D, Damsky, C
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 1979
Onderwerpen:	Research Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383692/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/288066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.6.2779
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