Human promyelocytic leukemia cells in culture differentiate into macrophage-like cells when treated with a phorbol diester.
When suspension cultures of human promyelocytic leukemia cells (line HL60) were treated with 12-O-tetradecanoylphorbol 13-acetate (TPA; 1.6-160 nM), more than 80% of the cells adhered to the plastic substrate within 24 hr. Within the same time period the immature azurophilic granulations typical of...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1979
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383692/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/288066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.6.2779 |
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