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Coordinate Nuclear Targeting of the FANCD2 and FANCI Proteins via a FANCD2 Nuclear Localization Signal

Fanconi anemia (FA) is a rare recessive disease, characterized by congenital defects, bone marrow failure, and increased cancer susceptibility. FA is caused by biallelic mutation of any one of sixteen genes. The protein products of these genes function cooperatively in the FA-BRCA pathway to repair...

詳細記述

保存先:
書誌詳細
主要な著者: Boisvert, Rebecca A., Rego, Meghan A., Azzinaro, Paul A., Mauro, Maurizio, Howlett, Niall G.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836817/
https://ncbi.nlm.nih.gov/pubmed/24278431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0081387
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