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Targeted overexpression of parathyroid hormone-related peptide in chondrocytes causes chondrodysplasia and delayed endochondral bone formation.

Parathyroid hormone-related peptide (PTHrP) was initially identified as a product of malignant tumors that mediates paraneoplastic hypercalcemia. It is now known that the parathyroid hormone (PTH) and PTHrP genes are evolutionarily related and that the products of these two genes share a common rece...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Weir, E C, Philbrick, W M, Amling, M, Neff, L A, Baron, R, Broadus, A E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38368/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8816783/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.19.10240
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