Brd4 Is Displaced from HPV Replication Factories as They Expand and Amplify Viral DNA

Replication foci are generated by many viruses to concentrate and localize viral DNA synthesis to specific regions of the cell. Expression of the HPV16 E1 and E2 replication proteins in keratinocytes results in nuclear foci that recruit proteins associated with the host DNA damage response. We show...

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Bibliografiske detaljer
Main Authors: Sakakibara, Nozomi, Chen, Dan, Jang, Moon Kyoo, Kang, Dong Wook, Luecke, Hans F., Wu, Shwu-Yuan, Chiang, Cheng-Ming, McBride, Alison A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836737/
https://ncbi.nlm.nih.gov/pubmed/24278023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003777
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