Brd4 Is Displaced from HPV Replication Factories as They Expand and Amplify Viral DNA

Replication foci are generated by many viruses to concentrate and localize viral DNA synthesis to specific regions of the cell. Expression of the HPV16 E1 and E2 replication proteins in keratinocytes results in nuclear foci that recruit proteins associated with the host DNA damage response. We show...

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Bibliographische Detailangaben
Hauptverfasser: Sakakibara, Nozomi, Chen, Dan, Jang, Moon Kyoo, Kang, Dong Wook, Luecke, Hans F., Wu, Shwu-Yuan, Chiang, Cheng-Ming, McBride, Alison A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836737/
https://ncbi.nlm.nih.gov/pubmed/24278023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003777
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