Brd4 Is Displaced from HPV Replication Factories as They Expand and Amplify Viral DNA

Replication foci are generated by many viruses to concentrate and localize viral DNA synthesis to specific regions of the cell. Expression of the HPV16 E1 and E2 replication proteins in keratinocytes results in nuclear foci that recruit proteins associated with the host DNA damage response. We show...

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Autors principals: Sakakibara, Nozomi, Chen, Dan, Jang, Moon Kyoo, Kang, Dong Wook, Luecke, Hans F., Wu, Shwu-Yuan, Chiang, Cheng-Ming, McBride, Alison A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836737/
https://ncbi.nlm.nih.gov/pubmed/24278023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003777
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