Pathways-Driven Sparse Regression Identifies Pathways and Genes Associated with High-Density Lipoprotein Cholesterol in Two Asian Cohorts

Standard approaches to data analysis in genome-wide association studies (GWAS) ignore any potential functional relationships between gene variants. In contrast gene pathways analysis uses prior information on functional structure within the genome to identify pathways associated with a trait of inte...

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Détails bibliographiques
Auteurs principaux: Silver, Matt, Chen, Peng, Li, Ruoying, Cheng, Ching-Yu, Wong, Tien-Yin, Tai, E-Shyong, Teo, Yik-Ying, Montana, Giovanni
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836716/
https://ncbi.nlm.nih.gov/pubmed/24278029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003939
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