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Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression()
We present a new method for the detection of gene pathways associated with a multivariate quantitative trait, and use it to identify causal pathways associated with an imaging endophenotype characteristic of longitudinal structural change in the brains of patients with Alzheimer's disease (AD)....
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Academic Press
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3549495/ https://ncbi.nlm.nih.gov/pubmed/22982105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2012.08.002 |
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