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Identification of gene pathways implicated in Alzheimer's disease using longitudinal imaging phenotypes with sparse regression()

We present a new method for the detection of gene pathways associated with a multivariate quantitative trait, and use it to identify causal pathways associated with an imaging endophenotype characteristic of longitudinal structural change in the brains of patients with Alzheimer's disease (AD)....

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書誌詳細
主要な著者: Silver, Matt, Janousova, Eva, Hua, Xue, Thompson, Paul M., Montana, Giovanni
フォーマット: Artigo
言語:Inglês
出版事項: Academic Press 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3549495/
https://ncbi.nlm.nih.gov/pubmed/22982105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2012.08.002
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