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Noncovalent intermolecular crosslinks are produced by bleomycin reaction with duplex DNA.

Reaction of covalently closed circular PM2 bacteriophage DNA with the anticancer drug bleomycin produces nicked circular (form II) and linear duplex (form III) DNA [Lloyd, R.S., Haidle, C.W. & Robberson, D.L. (1978) Biochemistry 17, 1890-1896]. As the reaction proceeds, the frequencies of both f...

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Autores principales: Lloyd, R S, Haidle, C W, Robberson, D L
Formato: Artigo
Lenguaje:Inglês
Publicado: 1979
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC383670/
https://ncbi.nlm.nih.gov/pubmed/88734
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