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Histone deacetylase (HDAC) 1 and 2 are Essential for normal T cell Development and Genomic Stability in Mice

Histone deacetylase 1 and 2 (HDAC1/2) regulate chromatin structure as the catalytic core of the Sin3A, NuRD and CoREST co-repressor complexes. To better understand the key pathways regulated by HDAC1/2 in the adaptive immune system and inform their exploitation as drug targets, we have generated mic...

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Bibliografische gegevens
Hoofdauteurs: Dovey, Oliver M., Foster, Charles T., Conte, Nathalie, Edwards, Sally A., Edwards, Jennifer M., Singh, Rajinder, Vasilliou, George, Bradley, Allan, Cowley, Shaun M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836254/
https://ncbi.nlm.nih.gov/pubmed/23287868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-07-441949
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