Mechano-transduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer associated fibroblasts

To learn more about cancer-associated fibroblasts (CAFs), we have isolated fibroblasts from different stages of breast cancer progression and analysed their function and gene expression. These analyses reveal that activation of the YAP transcription factor is a signature feature of CAFs. YAP functio...

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Main Authors: Calvo, Fernando, Ege, Nil, Grande-Garcia, Araceli, Hooper, Steven, Jenkins, Robert P., Chaudhry, Shahid I., Harrington, Kevin, Williamson, Peter, Moeendarbary, Emad, Charras, Guillaume, Sahai, Erik
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836234/
https://ncbi.nlm.nih.gov/pubmed/23708000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2756
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