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Adenoviral Vector Expressing Murine β-Defensin 2 Enhances Immunogenicity of an Adenoviral Vector based H5N1 Influenza Vaccine in Aged Mice

The ability to resist infections and respond to vaccinations is greatly reduced in the older adult population owing to a general decline in innate and adaptive immune functions with aging. Over the years several strategies such as increasing the vaccine dose, number of immunizations and using adjuva...

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Main Authors: Vemula, Sai V., Pandey, Aseem, Singh, Neetu, Katz, Jacqueline M, Donis, Ruben, Sambhara, Suryaprakash, Mittal, Suresh K.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836052/
https://ncbi.nlm.nih.gov/pubmed/23892144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2013.07.008
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