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Increasing the power of association studies with affected families, unrelated cases and controls

When studying the genetics of inherited diseases, researchers often collect data on affected families, unrelated cases, and healthy controls. However, the joint analysis of such heterogeneous data is difficult, and the simpler analysis of homogeneous subsets is often suboptimal. For example, while c...

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Detalhes bibliográficos
Main Authors: Stewart, William C. L., Cerise, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836002/
https://ncbi.nlm.nih.gov/pubmed/24312115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00200
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