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Ketamine: synaptogenesis, immunomodulation and glycogen synthase kinase-3 as underlying mechanisms of its antidepressant properties

Major depressive disorder is an extremely debilitating condition affecting millions of people worldwide. Nevertheless, currently available antidepressant medications still have important limitations, such as a low response rate and a time lag for treatment response that represent a significant probl...

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Detalhes bibliográficos
Main Authors: Zunszain, P A, Horowitz, M A, Cattaneo, A, Lupi, M M, Pariante, C M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835937/
https://ncbi.nlm.nih.gov/pubmed/23877835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.87
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