Impact of Delay to Cryopreservation on RNA Integrity and Genome-Wide Expression Profiles in Resected Tumor Samples

The quality of tissue samples and extracted mRNA is a major source of variability in tumor transcriptome analysis using genome-wide expression microarrays. During and immediately after surgical tumor resection, tissues are exposed to metabolic, biochemical and physical stresses characterized as “war...

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Detalhes bibliográficos
Main Authors: Caboux, Elodie, Paciencia, Maria, Durand, Geoffroy, Robinot, Nivonirina, Wozniak, Magdalena B., Galateau-Salle, Françoise, Byrnes, Graham, Hainaut, Pierre, Le Calvez-Kelm, Florence
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835918/
https://ncbi.nlm.nih.gov/pubmed/24278187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079826
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