Hepatic-Specific Lipin-1 Deficiency Exacerbates Experimental Alcohol-Induced Steatohepatitis in Mice

Lipin-1 regulates lipid metabolism via its function as an enzyme in the triglyceride synthesis pathway and as a transcriptional co-regulatory protein and is highly up-regulated in alcoholic fatty liver disease. In the present study, using a liver specific lipin-1-deficient (lipin-1LKO) mouse model,...

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Detaylı Bibliyografya
Asıl Yazarlar: Hu, Ming, Yin, Huquan, Mitra, Mayurranjan S., Liang, Xiaomei, Ajmo, Joanne M., Nadra, Karim, Chrast, Roman, Finck, Brian N., You, Min
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835749/
https://ncbi.nlm.nih.gov/pubmed/23787969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26589
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