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Hepatic-Specific Lipin-1 Deficiency Exacerbates Experimental Alcohol-Induced Steatohepatitis in Mice
Lipin-1 regulates lipid metabolism via its function as an enzyme in the triglyceride synthesis pathway and as a transcriptional co-regulatory protein and is highly up-regulated in alcoholic fatty liver disease. In the present study, using a liver specific lipin-1-deficient (lipin-1LKO) mouse model,...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3835749/ https://ncbi.nlm.nih.gov/pubmed/23787969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26589 |
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