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Role of aldehydes in the toxic and mutagenic effects of nitrosamines
α-Hydroxynitrosamine metabolites of nitrosamines decompose to a reactive diazohydroxide and an aldehyde. To test the hypothesis that the aldehydes contribute to the harmful effects of nitrosamines, the toxic and mutagenic activity of three model methylating agents were compared in Chinese hamster ov...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3835663/ https://ncbi.nlm.nih.gov/pubmed/24066836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx400196j |
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