TβRIII/β-arrestin2 regulates integrin α5β1 trafficking, function, and localization in epithelial cells

The type III TGF-β receptor (TβRIII) is a ubiquitous co-receptor for TGF-β superfamily ligands with roles in suppressing cancer progression, in part through suppressing cell motility. Here we demonstrate that TβRIII promotes epithelial cell adhesion to fibronectin in a β-arrestin2 dependent and TGF-...

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Hlavní autoři: Mythreye, Karthikeyan, Knelson, Erik H., Gatza, Catherine E., Gatza, Michael L., Blobe, Gerard C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835656/
https://ncbi.nlm.nih.gov/pubmed/22562249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.157
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