Further studies on the mode of action of the heme-controlled translational inhibitor: stimulating protein acts at level of binary complex formation.
Previous work has shown that (i) at physiological concentrations of eukaryotic initiation factor 2 (eIF-2), formation of the ternary complex eIF-2-GTP-Met-tRNAi, which precedes the assembly of a 40S initiation complex, requires the presence of eIF-2 stimulating protein (ESP) and (ii) the interaction...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1979
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383557/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/287053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.5.2163 |
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