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Reaction of nucleosome DNA with dimethyl sulfate.

We have measured the effect of the histones in the nucleosome core particle on methylation of purines in nucleosome DNA by dimethyl sulfate. By using 32P terminally labeled nucleosome cores, we have examined the pattern of strand cleavage at methylated sites in the nucleosome DNA and compared it to...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: McGhee, J D, Felsenfeld, G
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1979
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383551/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/287052/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.5.2133
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