Constitutive Function of the Ikaros Transcription Factor in Primary Leukemia Cells from Pediatric Newly Diagnosed High-Risk and Relapsed B-precursor ALL Patients

We examined the constitutive function of the Ikaros (IK) transcription factor in blast cells from pediatric B-precursor acute lymphoblastic leukemia (BPL) patients using multiple assay platforms and bioinformatics tools. We found no evidence of diminished IK expression or function for primary cells...

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Main Authors: Uckun, Fatih M., Ma, Hong, Ishkhanian, Rita, Arellano, Martha, Shahidzadeh, Anoush, Termuhlen, Amanda, Gaynon, Paul S., Qazi, Sanjive
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835424/
https://ncbi.nlm.nih.gov/pubmed/24278314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080732
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