High Fat, High Calorie Diet Promotes Early Pancreatic Neoplasia in the Conditional Kras(G12D) Mouse Model

There is epidemiologic evidence that obesity increases the risk of cancers. Several underlying mechanisms, including inflammation and insulin resistance, are proposed. However, the driving mechanisms in pancreatic cancer are poorly understood. The goal of the present study was to develop a model of...

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Autori principali: Dawson, David W., Hertzer, Kathleen, Moro, Aune, Donald, Graham, Chang, Hui-Hua, Go, Vay Liang, Pandol, Steven J., Lugea, Aurelia, Gukovskaya, Anna S., Li, Gang, Hines, Oscar J., Rozengurt, Enrique, Eibl, Guido
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835151/
https://ncbi.nlm.nih.gov/pubmed/23943783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-13-0065
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