An Exploratory Dose-Escalating Study Investigating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Intravenous Atacicept in Patients with Systemic Lupus Erythematosus

Atacicept, a recombinant fusion protein containing the extracellular, ligand-binding portion of the transmembrane activator and calcium modulator and cyclophilin-ligand interactor receptor, and the Fc portion of human immunoglobulin (Ig) G, is designed to block the activity of B-lymphocyte stimulato...

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Hlavní autoři: Pena-Rossi, C, Nasonov, E, Stanislav, M, Yakusevich, V, Ershova, O, Lomareva, N, Saunders, H, Hill, J, Nestorov, I
Médium: Artigo
Jazyk:Inglês
Vydáno: SAGE Publications 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835146/
https://ncbi.nlm.nih.gov/pubmed/19395457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0961203309102803
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