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Isolation of lysosomal α-mannosidase mutants of Chinese hamster ovary cells

A method is presented for detection of lysosomal hydrolase activity in situ in colonies of Chinese hamster ovary cells. This method was used to screen for mutants deficient in lysosomal α-mannosidase. Mutagenized cells were replicated onto filter papers [Esko, J. D. & Raetz, C. R. H. (1978) Proc. Na...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
第一著者: Robbins, April R.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 1979
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383502/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/287030/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.4.1911
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