Mutations in cyclic AMP-dependent protein kinase and corticotropin (ACTH)-sensitive adenylate cyclase affect adrenal steroidogenesis.

Two groups of mutant clones were isolated from YI adrenocortical tumor cells. One group, Y1(Kin), exhibited altered cytosolic cyclic AMP-dependent protein kinase activity; the second group, Y1(Cyc), exhibited diminished corticotropin-responsive adenylate cyclase activity. Steroidogenic responses to...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Rae, P A, Gutmann, N S, Tsao, J, Schimmer, B P
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1979
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC383499/
https://ncbi.nlm.nih.gov/pubmed/221910
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