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Synthesis of piperlogs and analysis of their effects on cells

Piperlongumine (PL) is a naturally occurring small molecule previously shown to induce cell death preferentially in cancer cells relative to non-cancer cells. An initial effort to synthesize analogs highlighted the reactivities of both of piperlongumine's α,β-unsaturated imide functionalities a...

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Hlavní autoři: Boskovic, Zarko V., Hussain, Mahmud M., Adams, Drew J., Dai, Mingji, Schreiber, Stuart L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834962/
https://ncbi.nlm.nih.gov/pubmed/24273350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2013.05.080
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