Potent antitumor activity of the novel HSP90 inhibitors AUY922 and HSP990 in neuroendocrine carcinoid cells

The heat shock protein (HSP) 90 chaperone machine involved in numerous oncogenic signaling pathways is over-expressed in cancer cells and is currently being evaluated for anticancer therapy. Neuroendocrine tumors (NETs) of the gastroenteropancreatic (GEP) system comprise a heterogeneous group of tum...

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Hauptverfasser: ZITZMANN, KATHRIN, AILER, GALINA, VLOTIDES, GEORGE, SPOETTL, GERALD, MAURER, JULIAN, GÖKE, BURKHARD, BEUSCHLEIN, FELIX, AUERNHAMMER, CHRISTOPH J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834873/
https://ncbi.nlm.nih.gov/pubmed/24100469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2013.2130
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