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Identifying subgroup markers in heterogeneous populations

Traditional methods that aim to identify biomarkers that distinguish between two groups, like Significance Analysis of Microarrays or the t-test, perform optimally when such biomarkers show homogeneous behavior within each group and differential behavior between the groups. However, in many applicat...

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Détails bibliographiques
Auteurs principaux: de Ronde, Jorma J., Rigaill, Guillem, Rottenberg, Sven, Rodenhuis, Sjoerd, Wessels, Lodewyk F. A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834840/
https://ncbi.nlm.nih.gov/pubmed/24062158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt845
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