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Conformational transitions in human translin enable nucleic acid binding

Translin is a highly conserved RNA- and DNA-binding protein that plays essential roles in eukaryotic cells. Human translin functions as an octamer, but in the octameric crystallographic structure, the residues responsible for nucleic acid binding are not accessible. Moreover, electron microscopy dat...

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Bibliografiske detaljer
Main Authors: Pérez-Cano, Laura, Eliahoo, Elad, Lasker, Keren, Wolfson, Haim J., Glaser, Fabian, Manor, Haim, Bernadó, Pau, Fernández-Recio, Juan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834833/
https://ncbi.nlm.nih.gov/pubmed/23980029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt765
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