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Conformational transitions in human translin enable nucleic acid binding
Translin is a highly conserved RNA- and DNA-binding protein that plays essential roles in eukaryotic cells. Human translin functions as an octamer, but in the octameric crystallographic structure, the residues responsible for nucleic acid binding are not accessible. Moreover, electron microscopy dat...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834833/ https://ncbi.nlm.nih.gov/pubmed/23980029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt765 |
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