Homology-mediated end-capping as a primary step of sister chromatid fusion in the breakage-fusion-bridge cycles

Breakage-fusion-bridge (BFB) cycle is a series of chromosome breaks and duplications that could lead to the increased copy number of a genomic segment (gene amplification). A critical step of BFB cycles leading to gene amplification is a palindromic fusion of sister chromatids following the rupture...

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Detalhes bibliográficos
Main Authors: Marotta, Michael, Chen, Xiongfong, Watanabe, Takaaki, Faber, Pieter W., Diede, Scott J., Tapscott, Stephen, Tubbs, Raymond, Kondratova, Anna, Stephens, Robert, Tanaka, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834830/
https://ncbi.nlm.nih.gov/pubmed/23975201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt762
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