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Lack of effect of ODQ does not exclude cGMP signalling via NO-sensitive guanylyl cyclase
BACKGROUND AND PURPOSE: Nitric oxide (NO) is known to activate NO-sensitive guanylyl cyclase (NO-GC) and to elicit cGMP production. However, NO has also been proposed to induce cGMP-independent effects. It is accepted practice to use specific NO-GC inhibitors, such as ODQ or NS2028, to assess cGMP-d...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Blackwell Publishing Ltd
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3834756/ https://ncbi.nlm.nih.gov/pubmed/23763290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12275 |
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