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Spinal actions of ω-conotoxins, CVID, MVIIA and related peptides in a rat neuropathic pain model

BACKGROUND AND PURPOSE: Antagonists of the N-type voltage gated calcium channel (VGCC), Ca(v)2.2, have a potentially important role in the treatment of chronic neuropathic pain. ω-conotoxins, such MVIIA and CVID are effective in neuropathic pain models. CVID is reported to have a greater therapeutic...

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Main Authors: Jayamanne, A, Jeong, H J, Schroeder, C I, Lewis, R J, Christie, M J, Vaughan, C W
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834750/
https://ncbi.nlm.nih.gov/pubmed/23713957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12251
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