Interactions of a photosensitive analog of cholesterol with hydroxymethylglutaryl-CoA reductase (NADPH) and acyl-CoA:cholesterol acyltransferase

25-Azido[25-(3)H]norcholesten-3β-ol, a radioactive photosensitive analog of cholesterol, was synthesized as a probe to study lipid-protein interactions [Stoffel, W. & Klotzbücher, R. (1978) Hoppe-Seyler's Z. Physiol Chem. 359, 199-209]. Upon UV irradiation a reactive nitrene is generated which can i...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Heller, Renu A., Klotzbücher, Rainer, Stoffel, Wilhelm
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1979
Assuntos:	Biological Sciences: Biochemistry
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383462/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/287013/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.4.1721
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