Interactions of a photosensitive analog of cholesterol with hydroxymethylglutaryl-CoA reductase (NADPH) and acyl-CoA:cholesterol acyltransferase
25-Azido[25-(3)H]norcholesten-3β-ol, a radioactive photosensitive analog of cholesterol, was synthesized as a probe to study lipid-protein interactions [Stoffel, W. & Klotzbücher, R. (1978) Hoppe-Seyler's Z. Physiol Chem. 359, 199-209]. Upon UV irradiation a reactive nitrene is generated which can i...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1979
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC383462/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/287013/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.76.4.1721 |
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