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A depot-forming glucagon-like peptide-1 fusion protein reduces blood glucose for five days with a single injection

Peptide drugs are an exciting class of pharmaceuticals for the treatment of a variety of diseases; however, their short half-life dictates multiple and frequent injections causing undesirable side-effects. Herein, we describe a novel peptide delivery system that seeks to combine the attractive featu...

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Detalhes bibliográficos
Main Authors: Amiram, M., Luginbuhl, K. M., Li, X., Feinglos, M. N., Chilkoti, A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834218/
https://ncbi.nlm.nih.gov/pubmed/23928357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.07.021
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