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Injectable protease-operated depots of glucagon-like peptide-1 provide extended and tunable glucose control

Peptide drugs are an exciting class of pharmaceuticals increasingly used for the treatment of a variety of diseases; however, their main drawback is a short half-life, which dictates multiple and frequent injections and an undesirable “peak-and-valley” pharmacokinetic profile, which can cause undesi...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Amiram, Miriam, Luginbuhl, Kelli M., Li, Xinghai, Feinglos, Mark N., Chilkoti, Ashutosh
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3581961/
https://ncbi.nlm.nih.gov/pubmed/23359691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1214518110
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